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Research Lab Specialist II - Aplenc Lab

Children's Hospital of Philadelphia
United States, Pennsylvania, Philadelphia
Jun 16, 2025

SHIFT:

Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP's Commitment to Diversity, Equity, and Inclusion

CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children. We strongly encourage candidates of all races, colors, ethnicities, religions, perspectives, sexes, backgrounds, and lived experiences to apply.

A Brief Overview
This role participates in a planned research projects by performing research protocols. Works independently and self-directed while providing advanced guidance and technical training to other lab staff. Possesses a specialized education in the biological or chemical sciences and is required to consistently exercise appropriate situational discretion and sound scientific judgment in execution, interpretation of experiments, and interpretation of data derived.

About the Laboratory

Dr. Richard Aplenc, MD, PhD, Professor of Pediatrics and Epidemiology at the Perelman School of Medicine at the University of Pennsylvania, AVP and Chief Clinical Research Officer, and The Mai and Harry F. West Endowed Chair in Pediatric Research at The Children's Hospital of Philadelphia, is seeking a talented and strongly self-motivated individual to join his collaborative team as a Research Lab Specialist II. Dr. Aplenc's work aims to improve clinical outcomes for pediatric acute myeloid leukemia (AML) patients through translational, patient-centered outcomes research, and large data projects. One specific area of Dr. Aplenc's research focuses on the discovery of novel therapeutic targets in pediatric AML through a proteogenomics approach.

The Research Lab Specialist II will work closely with senior scientific staff and will participate in planned research projects by performing experimental procedures with minimal supervision. Successful candidates will have a BS in Biology, Biochemistry, Chemistry, or a related field. Prior experience working or volunteering in a basic science laboratory is strongly preferred. This position is intended for individuals interested in a career in basic or translational sciences, with a desire to make meaningful scientific contributions as part of a dynamic team. The Research Lab Specialist II will have strong technical skills and excellent computer skills. Routine responsibilities may include:

  • Lab inventory management
  • Specimen transport/shipping
  • Clinical specimen processing
  • DNA/RNA/protein extraction
  • DNA cloning
  • RNA sequencing
  • Proteomics work
  • Cell/tissue culture work
  • Flow cytometry

The Research Lab Specialist II will have an opportunity to be trained in more advanced scientific techniques.

What you will do

  • Performs lab tests which require the analysis of results and interpretation of methods
  • Plans and develops specific research protocols and procedures.
  • Develops & troubleshoots new techniques and ideas.
  • Composes methods and sets-up protocols accurately, based on guidance provided by the PI, program director or senior scientist. Independently modifies methods and protocols when required.
  • Formulates and performs complex lab experiments, analyzes data and reports outcomes
  • Presents & discusses work at weekly lab meetings
  • Prepares laboratory reagents and monitors and maintains inventory
  • Performs calculations and maintains appropriate log books and lab notebooks
  • Maintains laboratory equipment, develops safety procedures and compliance records.
  • Research journals, papers and other scientific publications for pertinent information
  • Prepares data for publication or presentation at national/international symposia (presentation in papers, grant applications, and conferences)
  • May be called upon to present at national symposia.
  • Oversees junior staff and/or laboratory workflow.
  • Will perform independently various lab administrative tasks / functions.

Education Qualifications

  • Bachelor's Degree - Required
  • Master's Degree - Preferred

Experience Qualifications

  • At least five (5) years of directly relevant post grad scientific lab experience - Required
  • At least seven (7) years of directly relevant post grad scientific lab experience - Preferred or
  • At least four (4) years of directly relevant classroom and/or post grad scientific lab experience - Preferred

Skills and Abilities

  • Expert knowledge in the use of a wide variety of lab techniques, research equipment and research related software (Required proficiency)
  • Excellent verbal and written communications skills (Required proficiency)
  • Excellent organizational skills (Required proficiency)
  • Excellent critical thinking / problem-solving skills (Required proficiency)
  • Excellent analytical skills (Required proficiency)

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, professionals working onsite-at any CHOP location, for any portion of time-must be vaccinated for COVID-19. Learn more.

EEO / VEVRAA Federal Contractor | Tobacco Statement

SALARY RANGE:

$61,360.00 - $78,230.00 Annually

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

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At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.

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