Scientist In Vivo Immunology

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At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we've invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK's long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.

In the plan to create a new hub for mRNA-based vaccine discovery in Cambridge, we are building new laboratories that will be focused on the development of state-of-the-art methods that will be supporting deep product understanding, process and product development, as well as testing of pre-clinical and clinical samples for new vaccines.

The Scientist in the In Vivo Immunology team will support preclinical in vivo studies and will represent the project team in spearheading GSK's innovation of novel viral vaccines and platform programs. You will have the opportunity to support the in vivo efforts on multiple viral vaccine programs and platforms within GSK and with external partners in a collaborative and matrix team. You will help design and write in vivo study protocols, coordinate and initiate preclinical studies, conduct experiments and analyze experimental data pertaining to the understanding of cellular mediated immune responses and humoral immune responses from novel vaccine candidates, formulations, and platforms.

Key Responsibilities:

This role will provide you with the opportunity to lead key activities and to progress your career based on performance. The responsibilities include the following:

• As a preclinical in vivo study point of contact, you will work in a matrix team to support the identification of novel vaccine candidates and support platform development.

• Help design, plan, conduct, coordinate, monitor, and analyze in vivo studies for vaccine and platform programs.

• Schedule, manage and track the life cycle of in vivo studies.

• Conduct dosing, perform IVIS imaging, collect tissues; be trained and experienced in animal handling, sample collection, and surgical procedures.

• Ensure adherence to GSK and regulatory requirements for compliance with IACUC guidelines through writing and reviewing in vivo study protocols.

• Highly experienced in flow cytometry, particularly in characterizing immune responses for preclinical immunogenicity or challenge studies.

• Strong scientific knowledge to develop new flow cytometry panels and troubleshoot experiments.

• Analyze experimental data and document them in detail using an electronic notebook

• Prepare and document study protocols and final study reports as an author.

• Contribute to patent filing, IND submissions, and scientific publications.

• Present study plans and results at project meetings.

• Develop new experimental techniques based on project needs.

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

*Ph.D., M.S., or B.S. degree in immunology or a related field. The required post-graduate work experience is 0-1 years for a Ph.D., 2+ years for an M.S., and 4+ years for a B.S.

*2 or more years of experience in conducting in vivo animal studies within the fields of vaccines, infectious diseases, or immunology.

*Experience working with 10 color or more flow cytometry.

Experience in documentation of study protocols and reports.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Experience with immune-response related readout methods such as ELISA, Flow, Luminex, or qPCR methodologies.

• Experience working with various cross functional teams within a heavily matrixed organization.

• A collaborative team player with strong interpersonal skills

• Deep understanding of immunology.

• Worked in a matrix team.

• Detail-oriented with the agility to balance multiple projects with short timelines.

• Excellent communication and writing skills.

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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