Research Technician I

SHIFT:

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means.

A Brief Overview

This entry-level research technical role participates in planned research projects by performing research protocols, experimental procedures and other laboratory tasks under direct supervision.

Eugene Khandros, MD, PhD, a pediatric hematologist physician scientist focused on developing new therapies for sickle cell disease, beta thalassemia, and other red blood cell disorders, is looking for a Research Technician I to start in the spring/summer of 2026.

There are two main projects currently in the lab:

1)Chromatin remodeling enzymes in red blood cell development and hemoglobin transcriptional regulation.

2)Preclinical development of new gene therapy products for red blood cell disorders.

The work will involve cell culture of human red blood cell precursors, genetic editing using CRISPR technology, and their analysis using flow cytometry and molecular biology techniques, as well as use of mouse models of sickle cell disease and thalassemia. Familiarity with mouse work, mammalian cell culture, flow cytometry, and basic molecular biology techniques such as western blot analysis, PCR, and gene cloning is preferred. The ideal applicant will be a team player, work independently but with regular communication with the PI, have strong organizational and data analysis skills, and willing to make a 2-year commitment to this research. For interested candidates, there will also be opportunities for clinical shadowing in a pediatric hematology clinic.

What you will do

• Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee.
• Performs research procedures on experimental samples as directed
• Records and checks experiments/results for completeness and accuracy
• Performs calculations and maintains appropriate log and lab notebooks
• Performs tasks that may require minimal familiarity with fundamental techniques and lab equipment
• Assists in care of lab equipment
• Sterilizes and cleans glassware, and disposes of specimens, media and other materials using appropriate procedures
• Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
• Records results, organizes data and maintains lab notebook (physical or electronic) in an organized manner.
• Conducts literary searches as directed.

Education Qualifications

• High School Diploma / GED - Required
• Associate's Degree - Preferred
• Bachelor's Degree - Preferred

Experience Qualifications

• Related classroom or laboratory experience or successful completion of a technical training program (eg. Wistar, WPSI) - Required
• At least six (6) months Related classroom or laboratory experience or successful completion of a technical training program (eg. Wistar, WPSI) - Preferred

Skills and Abilities

• Basic understanding of lab procedures, protocols, and equipment.
• Strong verbal and written communications skills
• Strong organizational skills
• Solid critical thinking / problem-solving skills
• Solid analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.

EEO / VEVRAA Federal Contractor | Tobacco Statement

SALARY RANGE:

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

-------------------

At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.